Sixteen year old Kyla Star Duran has been missing for over three weeks.
Police say this isn't the first time she has run away but she's never been gone for this amount of time.
They believe she may be in the McAllen area.
Duran is 5'4and weighs about 160 lbs.
She was last seen with red hair and a piercing on her lower lip.
If you have any information, you are urged to call Mission Crimestoppers at (956) 581-TIPS.